Este fenómeno es conocido como efecto Jod-Basedow. El tratamiento con propiltiouracilo en dosis decrecientes consiguió un estado eutiroideo y mejoró la . Efectos de las hormomas tiroideas en el corazón. Visits . por el efecto de Wolff- Chaikoff, además de hipertiroidismo (mediado por el efecto de Jod-Basedow. de hipertiroidismo (mediado por el efecto de Jod-Basedow. En ambos casos, la causa subyacente es por la alta concentración de yodo en este medicamento.

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Wolff–Chaikoff effect

SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal’s impact. Iodine-induced hyperthyroidism due to non-ionic contrast radiography in the elderly.

Harrison’s Principles of Internal Medicine.

Finally, medications such as amiodarone may induce hypothyroidism mediated by the Wolff—Chaikoffas well as hyperthyroidism mediated by the Jod—Basedow eefcto.

Are you a health professional able to prescribe or dispense drugs? Iodide was used to treat hyperthyroidism before antithyroid drugs such as propylthiouracil and methimazole were developed.

By using this site, you agree to the Terms of Use and Privacy Policy. The Japanese-Brazilian thyroid study. The Jod-Basedow effect has also been seen as a side effect of administration of the iodine-containing contrast agents, or amiodaronean antiarrhythmic drug.

Thyroid function after hysterosalpingography using an oil-soluble iodinated contrast medium. Both hypothyroidism and hyperthyroidism increase the risk of coronary artery disease, left cardiomyopathy, electrophysiological abnormalities, and all-cause mortality. Subscriber If you already have your login data, please click here. Longo, Joseph Loscalzo In some ways the Jod-Basedow phenomenon is the opposite of the Wolff—Chaikoff effectwhich refers to the short period of thyroid-hormone suppression which happens in normal persons and in persons with thyroid disease, when comparatively large quantities of iodine or iodide are ingested.


This page was last edited on 10 Augustat Iodide induced hyperthyroidism with computed tomography contrast fluids.

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Do iodine-containing contrast media induce clinically relevant changes in thyroid function parameters of euthyroid patients within the first week? Cardiac and hemodynamic consequences of hyperthyroidism. The risk of CHD mortality and atrial fibrillation but not other outcomes in baseow hyperthyroidism is higher among patients with very low levels of thyrotropin. Effect of iodinated contrast media on thyroid function in adults. Se continuar a navegar, consideramos que aceita o seu uso.

The Wolff—Chaikoff effect is an effective means of rejecting a large quantity of imbibed iodide, and therefore preventing the thyroid from synthesizing large quantities of thyroid hormone.

Wolff–Chaikoff effect – Wikipedia

Rev Esp cardio ; This item has received. Mico Endocrinogo de la Clica Comfamiliar Risaralda. Clinically, this effect can lead jodd hypothyroidism. You can change the settings or obtain more information by clicking here. Hypothalamic—pituitary—thyroid axis Hypothalamic—pituitary—adrenal axis Hypothalamic—pituitary—gonadal axis Hypothalamic—pituitary—somatotropic axis Hypothalamic—pituitary—prolactin axis Hypothalamic—neurohypophyseal system Renin—angiotensin system.

From Wikipedia, the free encyclopedia. Larry Jameson, Anthony s. Mico basedoq en Medicina Interna. It is named after the German physician Karl Adolph von Basedow. N Engl J Med. The effect is rapid because of rapid inhibition of intrathyroid organification of iodide acute Wolff—Chaikoff effect and saturation of the iodide-transport mechanism. People who have Graves diseasetoxic multinodular goiteror various types of thyroid bwsedow are also at risk of Jod-Basedow effect when they ingest extra iodine.


Blood sugar regulation Calcium metabolism. Comprehensive Handbook of Iodine: Subclinical thyroid dysfunction and mortality: The Jod-Basedow effect does not basddow in persons with normal thyroid glands who ingest extra iodine in any form. Lancet ; Hyperthyroid subjects given iodide may experience a decrease in basal metabolic rate that is comparable to that seen after thyroidectomy.

Overall, hyperthyroidism is characterized by an increase in resting heart rate, blood volume, stroke volume, myocardial contractility, and ejection fraction.

Hyperthyreoserisiko bei Kontrastmittelun- tersuchungen. Animal experimental and clinical studies. In individuals with a normal thyroid, the gland eventually escapes from this inhibitory effect and iodide organification resumes; however, in patients with underlying autoimmune thyroid disease, ojd suppressive action of high iodide may persist. This page was last edited on 7 Augustat Bull N Y Acad Med. The Jod-Basedow effect also Jod-Basedow syndrome and Feecto phenomenon is hyperthyroidism following administration of iodine or iodide, [1] either as a dietary supplement or as contrast medium.

Med Clin North Am ;96 2: Cardiac preload is decreased due to impaired efexto function. Prevalence of thyroid dysfunction and effect of contrast medium on thyroid metabolism in cardiac patients undergoing coronary angiography. Subscribe to our Newsletter.